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Human neuroblastoma cells with MYCN amplification are selectively resistant to oxidative stress by transcriptionally up-regulating glutamate cysteine ligase. J Neurochem. 2010 Feb 17; Authors: de Tudela MV, Delgado-Esteban M, Cuende J, Bolaños JP, Almeida A Abstract Neuroblastoma is a sympathetic...
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Nuclear factor-kappaB activation regulates Cyclooxygenase-2 induction in human astrocytes in response to CXCL12: Role in neuronal toxicity. J Neurochem. 2010 Feb 17; Authors: Alvarez S, Blanco A, Fresno M, Muñoz-Fernández MA Abstract Neurodegenerative and neuroinflammatory disorders...
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Related Articles Expression of CXCL10 in cultured cortical neurons. J Neurochem. 2010 Feb;112(3):703-14 Authors: Vinet J, de Jong EK, Boddeke HW, Stanulovic V, Brouwer N, Granic I, Eisel UL, Liem RS, Biber K Chemokines expressed in neurons are important mediators in neuron-neuron and neuron-glia signaling...
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Related Articles Structural and functional characterization of a novel FE65 protein product up-regulated in cognitively impaired FE65 knockout mice. J Neurochem. 2010 Jan;112(2):410-9 Authors: Cool BH, Zitnik G, Martin GM, Hu Q FE65 is a multi-modular adaptor protein that binds the cytoplasmic tail of...
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Related Articles A novel mTOR activating protein protects dopamine neurons against oxidative stress by repressing autophagy related cell death. J Neurochem. 2010 Jan;112(2):366-76 Authors: Choi KC, Kim SH, Ha JY, Kim ST, Son JH Our previous microarray analysis identified a neuroprotective protein Oxi...
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Related Articles Single-nucleotide polymorphism (A118G) in exon 1 of OPRM1 gene causes alteration in downstream signaling by mu-opioid receptor and may contribute to the genetic risk for addiction. J Neurochem. 2010 Jan;112(2):486-96 Authors: Deb I, Chakraborty J, Gangopadhyay PK, Choudhury SR, Das S...
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Related Articles Induction of dystrophin Dp71 expression during neuronal differentiation: opposite roles of Sp1 and AP2alpha in Dp71 promoter activity. J Neurochem. 2010 Jan;112(2):474-85 Authors: Morales-Lázaro SL, González-Ramírez R, Gómez P, Tapia-Ramírez...
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METALLOCORROLES AS CYTOPROTECTIVE AGENTS AGAINST OXIDATIVE AND NITRATIVE STRESS IN CELLULAR MODELS OF NEURODEGENERATION. J Neurochem. 2010 Jan 24; Authors: Kupershmidt L, Okun Z, Amit T, Mandel S, Saltsman I, Mahammed A, Bar-Am O, Gross Z, Youdim MB Water-soluble iron, and manganese(III) complexes of...
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1-Benzyl-1,2,3,4-tetrahydroisoquinoline binds with tubulin beta, a substrate of parkin, and reduces its polyubiquitination. J Neurochem. 2010 Jan 8; Authors: Kohta R, Kotake Y, Hosoya T, Hiramatsu T, Otsubo Y, Koyama H, Hirokane Y, Yokoyama Y, Ikeshoji H, Oofusa K, Suzuki M, Ohta S Abstract Substances...
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The neuron-specific isoform of GSK-3beta is required for axon growth. J Neurochem. 2010 Jan 12; Authors: Castaño Z, Gordon-Weeks PR, Kypta RM ABSTRACT Glycogen synthase kinase-3 (GSK-3) has become an important target for the treatment of mood disorders and neurodegenerative disease. It comprises...
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Plumbagin, a Novel Nrf2/ARE Activator, Protects Against Cerebral Ischemia. J Neurochem. 2009 Dec 17; Authors: Son TG, Camandola S, Arumugam TV, Cutler RG, Telljohann RS, Mughal MR, Moore TA, Yu QS, Johnson DA, Johnson JA, Greig NH, Mattson MP Abstract Many phytochemicals function as noxious agents that...
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Related Articles Suppression of APP-containing vesicle trafficking and production of beta-amyloid by AID/DHHC-12 protein. J Neurochem. 2009 Dec;111(5):1213-24 Authors: Mizumaru C, Saito Y, Ishikawa T, Yoshida T, Yamamoto T, Nakaya T, Suzuki T The metabolism of amyloid beta-protein precursor (APP) is...
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Related Articles Hypoxia Protects Neuronal Cells from Human Prion Protein fragment-induced Apoptosis. J Neurochem. 2009 Nov 16; Authors: Seo JS, Seol JW, Moon MH, Jeong JK, Lee YJ, Park SY Prion diseases are neurodegenerative disorders characterized by the accumulation of an abnormal isoform of the prion...
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ATRA inhibits ceramide kinase transcription in a human neuroblastoma cell line, SH-SY5Y cells: the role of COUP-TFI. J Neurochem. 2009 Nov 7; Authors: Murakami M, Ito H, Hagiwara K, Yoshida K, Sobue S, Ichihara M, Takagi A, Kojima T, Tanaka K, Koizumi-T K, Kyogashima M, Suzuki M, Banno Y, Nozawa Y, Murate...
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Related Articles NO-flurbiprofen reduces amyloid-beta, is neuroprotective in cell culture, and enhances cognition in response to cholinergic blockade. J Neurochem. 2009 Nov;111(3):766-76 Authors: Abdul-Hay SO, Luo J, Ashghodom RT, Thatcher GR The non-steroidal anti-inflammatory drug flurbiprofen is a...