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Arsenite-induced apoptosis of human neuroblastoma cells requires p53 but occurs independently of c-Jun. Neuroscience. 2012 Jan 8; Authors: Keim A, Rössler OG, Rothhaar TL, Thiel G Abstract Arsenite treatment of human SH-SY5Y neuroblastoma cells leads to an upregulation of caspase-3/7 activity and to...
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Mesenchymal stem cells rescue the Alzheimer's disease cell model from cell death induced by misfolded truncated tau. Neuroscience. 2011 Oct 13;193:330-7 Authors: Zilka N, Zilkova M, Kazmerova Z, Sarissky M, Cigankova V, Novak M Abstract We have developed a stably transfected human cell model for...
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Lithium attenuates bupivacaine-induced neurotoxicity in vitro through phosphatidylinositol-3-kinase/threonine-serine protein kinase B- and ERK-dependent mechanisms. Neuroscience. 2012 Jan 3; Authors: Wang Z, Shen J, Wang J, Lu T, Li C, Zhang X, Liu L, Ding Z Abstract Local anesthetics (LAs) are necessary...
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Impact of fumonisin B(1) on glutamate toxicity and low magnesium induced seizure activity in neuronal co-culture. Neuroscience. 2011 Dec 9; Authors: Domijan AM, Kovac S, Abramov AY Abstract Fumonisin B(1) (FB(1)) is a mycotoxin produced by Fusarium spp. mould that contaminates maize world-wide. Although...
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Interleukin-1 receptor associated kinases-1/4 inhibition protects against acute hypoxia/ischemia-induced neuronal injury in vivo and in vitro. Neuroscience. 2011 Sep 10; Authors: Yang YF, Chen Z, Hu SL, Hu J, Li B, Li JT, Wei LJ, Qian ZM, Lin JK, Feng H, Zhu G Abstract Neuronal Toll-like receptors (TLRs...
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Epigenetic mechanisms of amyloid-β production in anisomycin-treated SH-SY5Y cells. Neuroscience. 2011 Aug 3; Authors: Guo X, Wu X, Ren L, Liu G, Li L Oxidative stress and inflammation as the pathological components of Alzheimer's disease (AD) have been well understood. Among a diversity of mitogen...
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Neurotoxicity induced by dexamethasone in the human neuroblastoma SH-SY5Y cell line can be prevented by folic acid. Neuroscience. 2011 Jun 1; Authors: Budni J, Romero A, Molz S, Martín-de-Saavedra MD, Egea J, Del Barrio L, Tasca CI, Rodrigues AL, Lopéz MG Folic acid (folate) is a vitamin of the B-complex...
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Volatile anesthetic post-treatment induces protection via inhibition of glycogen synthase kinase 3β in human neuron-like cells. Neuroscience. 2011 Jan 27; Authors: Lin D, Li G, Zuo Z Application of the volatile anesthetic isoflurane during the early phase of reperfusion reduces ischemic heart and brain...
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Related Articles Cellular prion protein (PrP(c)) overexpression disturbs cellular homeostasis in SH-SY5Y neuroblastoma cells but does not alter p53 expression: a proteomic study. Neuroscience. 2010 Jun 11; Authors: Weiss E, Ramljak S, Asif AR, Ciesielczyk B, Schmitz M, Gawinecka J, Schulz-Schaeffer W...
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Related Articles MDMA causes a redistribution of serotonin transporter from the cell surface to the intracellular compartment by a mechanism independent of p38 MAPK activation. Neuroscience. 2010 Mar 15; Authors: Kivell B, Day D, Bosch P, Schenk S, Miller J 3,4-Methylenedioxymethamphetamine (MDMA) causes...
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Haloperidol Disrupts Lipid Rafts and Impairs Insulin Signaling in SH-SY5Y Cells. Neuroscience. 2010 Jan 29; Authors: Sánchez-Wandelmer J, Dávalos A, de la Peña G, Cano S, Giera M, Canfrán-Duque A, Bracher F, Martín-Hidalgo A, Fernández-Hernando C...
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Enhanced vulnerability of PARK6 patient skin fibroblasts to apoptosis induced by proteasomal stress. Neuroscience. 2009 Dec 30; Authors: Klinkenberg M, Thurow N, Gispert S, Ricciardi F, Eich F, Prehn JH, Auburger G, Kögel D Proteasomal dysfunction and apoptosis are major hallmarks in the pathophysiology...
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Related Articles Dexamethasone Attenuated Bupivacaine-Induced Neuron Injury in vitro through an Akt-Dependent Mechanism. Neuroscience. 2009 Dec 25; Authors: Ma R, Wang X, Lu C, Li C, Cheng Y, Ding G, Liu L, Ding Z BACKGROUND:: Bupivacaine is one of the amide type local anesthetics and is widely used...
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Related Articles Synphilin-1 exhibits trophic and protective effects against Rotenone toxicity. Neuroscience. 2009 Oct 23; Authors: Li X, Liu Z, Tamashiro K, Shi B, Rudnicki DD, Ross CA, Moran TH, Smith WW Synphilin-1 is a cytoplasmic protein with unclear function. Synphilin-1 has been identified as...
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Related Articles Phospholipids Block NF-kappaB and Tau Phosphorylation and Inhibit Amyloid-beta Secretion in Human Neuroblastoma Cells. Neuroscience. 2009 Sep 26; Authors: Pandey NR, Sultan K, Twomey E, Sparks DL Inflammation and oxidative stress have been shown to play a critical role in the pathophysiology...