If your child has signs or symptoms that may suggest a neuroblastoma, the doctor will want to take a complete medical history to check for more symptoms. A physical exam can provide information about signs of a neuroblastoma and other health problems. For example, the doctor may find a child has high blood pressure or may be able to see or feel an abnormal mass in the body.

If symptoms and/or the results of the physical exam suggest a neuroblastoma (or other tumor) might be present, more involved tests will likely be done. These might include blood and urine tests, imaging tests, and biopsies. These tests are important because many of the symptoms and signs of neuroblastoma can also be caused by other cancers or by non-cancerous diseases.