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Antibody therapy is believed to rely on three different methods to kill neuroblastoma cells. These are called antibody dependent cell-mediated cytotoxicity (ADCC), complement mediated cytotoxicity (CMC), and passive immunotherapy using the anti-idiotypic network. The names sound much scarier that it...
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One of the great things about being a mouse is the fact that mice do not naturally get neuroblastoma. Mice develop antibodies that attach to neuroblastoma cells thus alerting the immune system to come and kill the tumor cell. Neuroblastoma cells get killed before they even get a chance to turn into tumors...